Construction of Secondary Metabolism Gene Cluster (SMGC) families was archived in a multi-step process. The initial step is the identification of SMGC which is done using an in-house wrapper for the SMURF algorithm [REF]. Protein products of the resulting SMGCs were compared to each other by alignment using BLASTp (BLAST+ suite version 2.2.27, e-value <= 10^-10).... Continue Reading →
Construction of protein families using BLAST alignments and single linkage. Analysis of core and pan genomes.
Construction of families of secondary metabolism gene clusters using a specialized comparison score and clustering.